Active immunization with human interleukin-15 induces neutralizing antibodies in non-human primates
نویسندگان
چکیده
منابع مشابه
Hypercalcemia Associated with a Human Squamous Neutralizing Antibodies to Human Interleukin 6 Reverse
Bone resorbing cytokines may be associated with abnormalities in bone cell function and calcium homeostasis in a number of pathological condi tions. One of these cytokines is interleukin 6 i II .-(>).which is a multifunc tional cytokine which has been shown to be associated with increased formation of bone resorbing osteoclasts in vitro. In this report, we dem onstrate that neutralizing antibod...
متن کاملExperiments with Non-human Primates
J Rehabil Med Suppl 41, 2003 DOI 10.1080/16501960310010124 In this laboratory we have developed a set of techniques that randomized controlled studies indicate can substantially reduce the motor deficit of patients with mild to moderately severe chronic strokes. The techniques, termed Constraint-Induced Movement therapy (CI therapy), involve motor restriction of the less-affected arm while at t...
متن کاملActive immunization with a Coxsackievirus A16 experimental inactivated vaccine induces neutralizing antibodies and protects mice against lethal infection.
Coxsackievirus A16 (CA16) is one of the main pathogens that cause hand, foot and mouth disease, which frequently occurs in young children. A small percentage of patients infected with CA16 may suffer from severe neurological complications that could also lead to death. Recent epidemiological data shows the increase in both the total number and the incidence rate of severe CA16-associated cases ...
متن کاملExperimental Field Studies with Non-human Primates Experimental Field Studies with Non-human Primates
One way to study language evolution is to compare human communication with closely related non-human primate species. This comparative approach has turned to be especially productive if subjects are studied under natural field conditions in which they have evolved. Various observation techniques have been developed, but field experiments are often needed to clarify underlying cause-effect relat...
متن کاملImmunization for HIV-1 Broadly Neutralizing Antibodies in Human Ig Knockin Mice
A subset of individuals infected with HIV-1 develops broadly neutralizing antibodies (bNAbs) that can prevent infection, but it has not yet been possible to elicit these antibodies by immunization. To systematically explore how immunization might be tailored to produce them, we generated mice expressing the predicted germline or mature heavy chains of a potent bNAb to the CD4 binding site (CD4b...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: BMC Immunology
سال: 2016
ISSN: 1471-2172
DOI: 10.1186/s12865-016-0168-6